Success Rate of IVF in Paaranu IVF Clinic
Paaranu IVF Clinic has been in existence for almost a decade (established 2011). We maintain success rates for various procedures on par with the best clinics in the world.
| TECHNIQUE | CLINICAL PREGNANCY RATE (%) |
|---|---|
| Intrauterine Insemination (IUI) | 22% |
| In vitro fertilization (IVF) | 55% |
| Intracytoplasmic sperm injection (ICSI) | 56% |
| Egg (oocyte) donation (OD) | 60% |
| Embryo donation (ED) | 72% |
| Gestational surrogacy (own eggs) | 44% |
| Gestational surrogacy (donor eggs) | 65% |
Recent Policy Changes
These days we are shifting our policy towards "FREEZE ALL" for all patients. This means that we would stimulate the ovaries, retrieve the eggs, fertilize them and freeze all the embryos. Embryo transfer would NOT be done in the stimulation cycle. In the next month, the endometrium is prepared with estrogens and other appropriate medication to improve its receptivity and frozen embryos are transferred once endometrium is ripe.
With the advent of the new technique of "vitrification" embryos can now be frozen and thawed safely (without any risk of damage by the freezing procedure). As a result of these two advances we are now able to optimize and increase success rates to around 50% per cycle. The cycle, of course, would now be of two months instead of the conventional one month. This is particularly advantageous in the following situations:
- Less eggs and Lesser no. of embryos (less than 3 embryos of grade 1).
- Patients with low AMH and poor responders (pooling of embryos).
- History of previous miscarriage / biochemical pregnancy
- History of previous ectopic pregnancy.
- Retrieval of more than 20 eggs (to avoid ovarian hyperstimulation).
- Endometrium (uterus lining) thin or < 7 mm in thickness.
- History of previous IVF failures
- Abnormal hormone levels (elevated progesterone) in the stimulation cycle
- Patients with polycystic ovaries
- Patients with endometriosis
IVF success rates have been quite steady for more than two decades now. With “Fresh” embryo transfer (transfer in the same cycle as the egg retrieval) pregnancy rates were in the range of @ 40-45% and after correcting for pregnancy losses and miscarriages, the net take home baby was in the range of 35-40%
Over the past one year, our centre made a gradual shift in policy towards “freeze-all embryos” in tune with some of the leading IVF clinics in the world.
This shows a clear 10% increase in pregnancy rates (especially ongoing pregnancies indicating a reduction in the number of miscarriages and other early pregnancy losses). This increase in pregnancy rate is due to a better state of “preparedness” of the womb to accept the embryo. In the fresh cycle, we cannot administer hormones or other medicines to improve the receptivity of the endometrium (thickness and quality) as these would interfere with the egg quality. This is easily done in the next month which is why the pregnancy rates are much higher with frozen embryos
To our mind, this is one of the most significant advances in the field of IVF technology resulting in a remarkable increase in pregnancy rates as compared to conventional IVF with fresh embryo transfer. Of course, we need more data and more international publications demonstrating similar results before advocating it as standard practice